Thursday, 9 July 2009

General Primary Pillar Post

Here goes:

Arthritis is a term that is often bandied about the internet and general conversation. It isn’t a good medical term, as it describes many symptoms and medical conditions, from aggressive auto-immune conditions (rheumatoid arthritis), where joint surfaces are attacked by the body’s defence system, to osteoarthritis, which is itself caused by numerous conditions, such as poor alignment of lower and upper legs at the knee (for example after the fracture of a bone, tendon or ligament. Doctors often call the condition an arthrosis if the condition wasn’t related to inflammation.

However, whatever the molecular cause of the arthritis, the result is a painful loss of friction-bearing surface, the hyaline cartilage, a natural, slippery, shock-absorbing natural material. When the bony surfaces that are below the cartilage rub together, the result is similar to running a car without oil, a grinding mess.

When this happens, the result is terrible pain, that is usually relieved partially by pain killers. Doctors will normally recommend implanting a joint.

However, many people have seen remarkable results by controlling just the diet.


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Competition analysis

After much knocking around, the keyphrase natural arthritis remedies has been chosen.

Arthritis as a search term has about 25 million entries. Looking at different combinations of keywords on Google's external keyword tool (Adwords), many opportunities seem to exist within the Arthritis niche. Arthritis has a monthly global search volume of 2.7 million, arthritis pain 111,000, arthritis therapies 22,000. However, these are hugely uncompetitive.

Analysis of the keyphrases shows that natural arthritis remedies has a search volume of 6,600:

















with competing pages of 490,000 on broad match (with Adwords adverts):















and 5,790 on exact match (also with Adwords ads):


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Finding a product to sell

Well, Clickbank has 15 arthritis-related products to sell:


















The first three seem quite popular, if not remarkable (gravity between 4 and 7), and products 1 and 3 are relevant to the chosen keyphrase: natural arthritis remedies.

















Number one product costs only $34, but gives $18.74 in Commission. The testimonials seem OK, but un-authoritative., but has several interesting, if not directly relevant bonuses.

Although not the best offer in the world, it seems a satisfactory starting point.

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Keyword Research

OK, so I've re-done my keyword research. Has anyone noticed that Google throws up different figures between searches, even a few minutes apart. So that doesn't matter much, but it does when your initial competition analysis shows 300,000 - 80 (broad - exact) when it should have been 5,000,000 - 11,000 (broad - exact). Surely 30 minutes doesn't make that much difference. Now re-starting my campaign along more competitive lines.

Google first look:



























So, I added Wonder wheel analysis in stages, too:














































This strongly suggests that treatments, therapies or remedies are the best 'buying' arthritis keyphrases based on the concept of pain relief.
Natural is a further keyphrase modifier - quite an in concept, I think.
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New Keyphrase

Started off creating Web 2.0 properties on the keyphrase Arthritis Therapies.

Looking more closely at the keyword research, I'm starting over - to the phrase natural arthritis remedies.

...now that will teach me to rush into things!!!!!

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About Me

Well I guess I should be following Howie's instructions.....

So I'm not a complete newbie - I've 'trying' for 18 months. I have lots of semi-built sites, flawed campaigns, Clickbank checks (cheques) that cost more than they were worth, blogs that are sadly un-updated....... My main failure is finding the time to get consistent traffic to my ideas. I have expertise in Regenerative Medicine, so i could call myself a REMARKABLE marketer from the point of view of my potential - I have the desire for IM, and a unique angle/knowledge/experience.

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Sunday, 5 July 2009

Autologous Chondrocyte Implantation

Having reviewd my brain (!!), I have a created a scientific pillar post. I intend to have an uber-technical one (below), and a more general, easy-to-understand one. These should be useful for driving traffic by vitue of the keywords contained in them. This is the technical one:

Osteoarthritis and Rheumatoid arthritis have completely different molecular origins, the latter being largely an auto-immune disease, the former having many origins, from simple mechanical defects to inflammatory.

Articular cartilage lesions, caused by trauma, osteochondritis disseccans or as a result of instability or abnormal loading are a common cause of disability, often associated with pain, reduction of joint mobility and loss of function, and can ultimately lead to osteoarthritis. Articular cartilage has a very limited intrinsic healing potential, related to the absence of vascularization and the presence of few and very specialized cells with low mitotic activity. Therefore, injury to the cartilage tissue still represents a major challenge for the orthopaedic surgeons.Traditional surgical techniques, that is palliative (e.g. lavage and debridement) or reparative options (e.g. bone marrow stimulation techniques), have shown variable success rates and carry a number of limitations. On the other hand, autologous chondrocyte implantation (injection of in vitro expanded autologous chondrocytes) has been proven to be clinically effective in the treatment of large, full thickness focal defects of the femoral condyle, including OCD. Recent evidence from prospective, controlled clinical studies comparing ACI with conventional treatments, in particular debridement, marrow stimulation techniques and mosaicplasty, suggests the superiority of ACI treatment, especially at long follow-up times. Despite the promising clinical results obtained so far, the use of ACI is associated with a number of limitations essentially correlated with the complexity of the surgical procedure, in particular the potential of cell leakage from the lesion site and the occurrence of periosteal hypertophy.Articular cartilage lesions, caused by trauma, osteochondritis disseccans or as a result of instability or abnormal loading are a common cause of disability, often associated with pain, reduction of joint mobility and loss of function, and can ultimately lead to osteoarthritis. Articular cartilage has a very limited intrinsic healing potential, related to the absence of vascularization and the presence of few and very specialized cells with low mitotic activity. Therefore, injury to the cartilage tissue still represents a major challenge for the orthopaedic surgeons.

Traditional surgical techniques, that is palliative (e.g. lavage and debridement) or reparative options (e.g. bone marrow stimulation techniques), have shown variable success rates and carry a number of limitations. On the other hand, autologous chondrocyte implantation (injection of in vitro expanded autologous chondrocytes) has been proven to be clinically effective in the treatment of large, full thickness focal defects of the femoral condyle, including OCD. Recent evidence from prospective, controlled clinical studies comparing ACI with conventional treatments, in particular debridement, marrow stimulation techniques and mosaicplasty, suggests the superiority of ACI treatment, especially at long follow-up times. Despite the promising clinical results obtained so far, the use of ACI is associated with a number of limitations essentially correlated with the complexity of the surgical procedure, in particular the potential of cell leakage from the lesion site and the occurrence of periosteal hypertophy.

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